Devic’s disease associated with anti-Ro/SSA antibodies
نویسندگان
چکیده
Neuromyelitis optica (NMO) and systemic inflammatory diseases are not mutually exclusive. Even when other autoantibodies are present, myelitis extending over 3 vertebral segments with NMO-IgG positivity discloses the diagnosis of NMO. We report the case of an isolated myelitis extending over 6 vertebral segments due to neuromyelitis optica (NMO). Despite the absence of optic nerve involvement, the absence of NMO-IgG in the blood and the presence of symptoms and autoantibodies suggestive of Sjögren syndrome, the diagnosis was founded on spinal magnetic resonance imaging and the detection of NMO-IgG specific antibodies in cerebrospinal fluid.
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Isotype switching and titer variation of anti-Ro/SSA antibodies over time in 100 patients with undifferentiated connective tissue disease (UCTD).
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